April 24, 2012

Astex Pharmaceuticals to Announce 2012 First Quarter Financial Results on April 30, 2012

DUBLIN, Calif., April 24, 2012 (GLOBE NEWSWIRE) -- Astex Pharmaceuticals, Inc. (Nasdaq:ASTX), a pharmaceutical company dedicated to the discovery and development of novel small molecule therapeutics, today announced that it will release its 2012 first quarter financial results on Monday, April 30, 2012. James S.J. Manuso, PhD, chairman and chief executive officer, and the Astex Pharmaceuticals management team will provide details of the Company's financial results and any revised outlook for the future.

A press release will be issued following the close of the market on April 30th. The Company will host a webcast conference call to discuss the results at 4:30 p.m. ET. A live webcast of the call will be available in the Investor Events section of the Company's website at www.astx.com. A webcast replay of the conference call will be available shortly following the event. Alternatively, you may access a replay of the conference call by dialing (855) 859-2056 (domestic) and (404) 537-3406 (international); the replay passcode number is 73568356.  The webcast replay will be available for 30 days, and the telephone replay will be available for 7 days.

About Astex Pharmaceuticals

Astex Pharmaceuticals is dedicated to the discovery and development of novel small molecule therapeutics with a focus on oncology. The Company is developing a proprietary pipeline of novel therapies and is creating de-risked products for partnership with leading pharmaceutical companies. Astex Pharmaceuticals developed Dacogen® (decitabine) for Injection and receives significant royalties on global sales.

For more information about Astex Pharmaceuticals, Inc., please visit http://www.astx.com.

The Astex Pharmaceuticals, Inc. logo is available at http://www.globenewswire.com/newsroom/prs/?pkgid=12273

CONTACT: Timothy L. Enns

         Astex Pharmaceuticals, Inc.

         Senior Vice President

         Corporate Communications & Marketing

         Tel: (925) 560-2810

         E-mail: tim.enns@astx.com



         Susanna Chau

         Astex Pharmaceuticals, Inc.

         Manager

         Investor Relations

         Tel: (925) 560-2845

         E-mail: susanna.chau@astx.com



         Alan Roemer

         The Trout Group

         Managing Director

         Tel: (646) 378-2945

         E-mail: aroemer@troutgroup.com



         Melanie Toyne-Sewell (Europe)

         Rebecca Skye Dietrich (US)

         College Hill

         Tel: +44 20 7866 7866

         Tel: (857) 241-0795

         E-mail: astex@collegehill.com

Astex Pharmaceuticals, Inc. logo

Source: Astex Pharmaceuticals, Inc.

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